Medical Monday: Breaking News from the World of Obstetrics and Gynecology

Efforts continue around the country to prevent changes to Title X funding. Title X funding is meant to supply federal funds for family planning and preventive health services. However, since those services have historically included birth control and abortion, the current administration is seeking to redirect these funds. In particular, the Trump administration would like to see those funds go to programs that promote abstinence only, which is not an evidenced based measure. Opponents of the changes including Planned Parenthood are arguiing that such charge are unconstitutional since they have not gone through a federal rule making process. 

The House has passed a bill allowing Medicaid to pay for inpatient drug treatment in case of cocaine and opioid addiction. The bill is contested on both sides, with some Democrats saying its focus it too narrow. 

The House has also passed more bills pertaining to the opioid crisis, mot notably by extending access to mental health and substance abuse disorder services to children and pregnancy women under CHIP, the Children’s Health Insurance Program. 

“Association Health Plans” are potentially bare bones health insurance plans which may be obtained by groups of small businesses even across state lines. The idea there is that lower cost can be achieved by forgoing benefits like birth control or pregnancy care, things which have been mandated under the affordable care act (ACA). Many feel the omission of what are now defined as “essential services” is short sighted and will contribute to the weakening of health care markets overall. 

A US District Judge has ruled in favor of two Christian Colleges to bar the enforcement of the contraceptive mandate as it applies to their University sponsored insurance. I understand that many Christians are opposed to abortion, and that many are also opposed to sex before marriage. However, what is the problem with contraception ? 

Many people are not aware of the Pregnancy Discrimination Act. It is a clause to Title VII of the Civil Rights Act of 1964 and is for the purpose of prohibiting “sex discrimination on the basis of pregnancy”. Pregnancy is a temporary disability in the eyes of the law. Violating employment law pertaining to pregnancy wold be treated like violating employment law pertaining to disability. The Act protects women not only during pregnancy, but also during “pregnancy, childbirth and related medical conditions”. 

Medical News

In England there is a public health program. In 2008, an HPV vaccination program was instituted. Ten years later, we cannot see that this has resulted in infections with the most serious HPV viruses, types 16 and 18 fell 86%. Experts speculate that the vaccine could lea to the eradication of HPV related diseases such as genital warts or cervical cancer. 

Focus on the American Maternal Mortality Crisis continues. New data continue to confirm what many have already observed, that black women die at three times the rate of white women from pregnancy related causes. May have suggested hypertension and racism are playing roles, as well as lesser access to quality care. 

New and sobering data are coming in about the common disorder we call “PCOS” or polycystic ovarian syndrome. PCO is complex of hormonal problems leading to problems with ovulation, ovarian cysts, and trouble with androgens, insulin and the processing of fats and carbohydrates. We used to think of PCO  as pertaining mainly to infertility, but PCO related infertility is quite treatable. However, now, more physicians like me are even more concerned about the downstream metabolic effects of this syndrome. The carbohydrate intolerance leads to obesity and the obesity leads to more carbohydrate intolerance. All of this leads tot higher BP and abnormal lipids, setting the patient up fro diabetes and heart disease later in life. In fact, we now know that about half of patients with untreated PCO will have diabetes before age 40. If you think you have PCO, please contact your doctor and ask to be referred for appropriate medical and lifestyle management. 

Obesity in pregnancy is known to be associated with an increased rate of a number of pregnancy and brith complications. However, it now appears, that offspring of obese mothers are considered a high risk population for endothelial cell dysfunction, meaning cardiovascular problems. In fact, either maternal smoking or obesity predisposes daughters with PCOS. When will the nation and the medical profession come to terms with the obesity epidemic ? 

Stay tuned for more news from the fascinating world of Obstetrics and Gynecology, here, next week on Medical Monday. 

Medical Monday: Breaking News from the World of Obstetrics and Gynecology

Policy News:

Medical and civil rights organizations have come together to oppose the detention of pregnant women by the agency on Immigration and Customs Enforcement (ICE). They have cited harmful effects on the health of these individuals due to lack of access to proper prenatal care and due to the high risk of rape while detained. 

Senator Tammy Duckworth (D-Illinois) has been the first Senator to have a baby while in office. Adequate lactation rooms were ensured through a measure by Senator Nancy Pelosi in 2008 so that breastfeeding Senators could comply with breastfeeding recommendations from the American Academy of Pediatrics. However, the post partum senator may have more difficulty attending votes unless the current rules barring children from the Senate floor are modified. 

The Trump administration has added two new exemptions to the individual mandate which is the rule that says people must carry individual health insurance or pay penalties. One is an exemption for those who live in a place with only one ACA (Affordable Care Act) insurance carrier whose coverage includes abortion services. On the basis of paying into a fund whose services include abortion, they can be exempted. I can see why people feel such consumers should not be obligated to use such a plan. I believe, however, that same anti-abortion consumer should be obligated to follow through with their execution of conscience and be required, under pain of penalty to buy private health insurance so that the rest of society does not end up footing the bill for their conscience driven but unfunded health care.  

The second exception the the individual mandate is nonsense. It is a “hardship” exemption. Who more than those under hardship need quality health care ? This particular exemption is a recipe for making the poor or those under hardship even poorer. And what does it gain? It gains political brownie points under the guise of freedom, and a better appearing Federal spreadsheet for this administration to tout to the voting taxpayers. We need to do a better job a making it clear to people that they stand to gain much more buying health insurance than they do forgoing it. 

Four abortion restricting laws have been passed by the 2017 Arkansas legislators. However, several influential groups have filed amicus briefs at the 8th Circuit Court of Appeals in St. Louis. One is the American College of Obstetricians and Gynecologists pertaining to the criminalization of “D & E”, the procedure dilation and curettage. This procedure is a safe and effective method for abortion, the safest in fact for the second trimester, and is used in many medically indicated cases where the patient’s life is at stake. 

The New York Times has reported that Scott Lloyd, the director of the Office of Refugee Resettlement keeps a spreadsheet of all detained unaccompanied minors who are pregnant and are requesting abortion. Lloyd has directed that this "captive audience" received non medical “counseling”  regarding their requests. Does anyone else view this as a misuse of power ? Does anyone else view this an incursion of a non-medical authority into the realm of medicine and counseling ?

Medical News: 

 Ever heard of the term “Previvor”? Me neither.  Previvors are those that know they carry a genetic mutation for cancer but have not yet developed cancer. Many are people who have discovered their mutation through non- medical genetic screening such as through the popular company “23 and me”. Others are those with family member with cancer who have been advised to do testing. Either way they are in a grey zone, and do not always get the care they need to address their relatively new predicament. Enter Dr. Heather Macdonald, an Obstetrician Gynecologist at Hoag Hospital in Newport Beach, California. She has created a special tailored program for these patients. It is called the “ Breast and Ovarian Cancer Prevention Program. In it she has outlined the possible ways to address risk, which may range from surgery, to medication to health maintenance strategies. 

The nation is finally mobilizing on the issue of maternal morbidity and mortality. Five states were in on the creation of the Alliance for Innovation on Maternal Health (AIM), California, Florida, Illinois ,Michigan, and Oklahoma. Texas, the nation’s worst offender, has now joined. The initial states have since seen significant decreases in maternal morbidity using protocols called “safety bundles”. 

Young women still suffer stigma even in the confines of an office visit. New research indicated fully half of teens and young women do not feel comfortable discussing sexually transmitted infections (STIs). Moreover, over a quarter lie to their caregivers about their sexual history. Separate research has shown that that the incidence of STIs is at a many decade high. Nonetheless, 62% of women under 25 do not consider themselves at risk for STIs. Only 40% use condoms. What might be a way to change all this ? 

A recent study published in Obstetrics and Gynecology indicates that marijuana does show up in the breastmilk of using mothers. Infants who breastfed exclusively ingested about 2.5 percent of the maternal dose and peaked one hour after smoking. ACOG’s position on marijuana in pregnancy and breastfeeding is as follows: 

There are “...concerns regarding impaired neurodevelopment, as well as maternal and fetal exposure to the adverse effects of smoking”. 

"There are insufficient data to evaluate the effects of marijuana use on infants during lactation and breastfeeding, and in the absence of such data, marijuana use is discouraged.”

Reference: 

https://www.acog.org/Clinical-Guidance-and-Publications/Committee-Opinions/Committee-on-Obstetric-Practice/Marijuana-Use-During-Pregnancy-and-Lactation

PCO or polycystic ovarian syndrome is a complex medical condition that comprises problems with ovulation, fertility, menstruation and excess male hormones, and problems with acne and unwanted hair growth. It also includes problems with carbohydrate metabolism and may lead to cardiovascular disease and diabetes. New research also indicates is is associated with a higher prevalence of several psychiatric conditions including depression and anxiety. 

Initial testing of a personalized vaccine against recurrent ovarian cancer cells is showing promise. A patient’s own dendrite cells (DC) are treated and given separately or together with other immunotherapy. The DC vaccine induced potent anti tumor T cell responses and was well tolerated, and was associated with a better prognosis. Further clinical testing is planned. 

New research in the Journal Menopause has unearthed a connection between the severity of menopausal symptoms and the risk of heart disease. The research found that increased symptoms such as hot flashes were associated with artery stiffness and dysfunction. This research may come to influence the way we think about postmenopausal hormone replacement therapy which reduces both symptoms and arterial dysfunction. 

The biggest news of the week may be that alcohol is not as safe as once previously believed. A new international study has shown that even one drink of beer or wine per day can increase the odds of hypertension, stroke and heart disease and significantly shorten life. Numerous national and international recommendations are likely to be changed based on this. 

Stay tuned this week for more exciting news from the world of Obstetrics and Gynecology. 

Medical Monday: Part Two

Medical Monday: Medical News Section 

Pregnancy related death continues to rise in at a fairly steady rate in the US. As of 2013, we sit at 17.3 women per 100,000 live births with a rage of about 12 per 100,000 for whites and 40 per 100,000 for blacks. Cardiovascular diseases of various kinds accounts for about 40% if these deaths. About 9% are due to pulmonary embolism, and 7% are related to high blood pressure and preeclampsia. The rest pertain to infection, hemorrhage and rare disorders like amniotic fluid embolism. 

Teen births are statistically high risk. It turns out that high teen birth rates cluster in certain cities. Analysis of the data shows these clusterings are not random and are not related to poverty to education. Most generally, the clusters are in the southern states, but they also exist in Denver, Fresno, and Yakima. San Antonio has the distinction of being the number one urban center with a teen pregnancy cluster. These findings my begin to help shed light on what is no doubt at least partly a cultural phenomenon. 

Breastfeeding has been touted has having numerous benefits, including health benefits to the mother. It turns out that prevention of uterus (endometrial) cancer is one of those benefits. Breastfeeding EVER confers an 11% reduction of risk. The longer the breastfeeding the more the risk was reduced, until risk reduction peaked at somewhere around 6-9 months of breastfeeding. 

Polycystic Ovary Syndrome (See PCO section HERE) is a complex of problems which include problems with ovulation (producing an egg), as well as obesity, excess male hormone, and difficulty metabolizing carbohydrate. A given patient may have one, all, or just a selection of the features of this varied disease. Generally, doctors have assumed that obesity and carbohydrate intolerance goes together. However new research has shown that even normal weight patients with PCO have have significant insulin resistance. This points for the need to counsel normal weight patients to eat a very high quality diet rich in protein, vegetables and fruit, and healthy fats. 

The overall incidence of depression in teens in higher than once previously believed, coming in at about 14% for those between 12-17. Of note, by 17, girls had a three fold higher incidence than boys. 

In the vice department, the news is sobering. New research from the Journal of Drug and Alcohol Dependence has shown that children born to women who smoke as few as 10 cigarettes per day have problems later in life. In particular, they have increased problems “learning and thinking”. 

The British Medical Journal has published research showing that even small amounts of alcohol produces changes in brain function which play out as poorer performance on language related tests. This data comes from research on 550 men and women over a 30 year period of time. 

Hard data is in from last year’s mosquito season in America (including Puerto Rico). Zika virus, which is transmitted by mosquito, produced birth defects in about 5% of babies who’s mothers became infected in pregnancy. This number was higher for those infected early, and lower for those infected late. We should learn even more this  year, and hopefully get one season closer to a vaccine for this dreaded disease. 

For those in Zika- vulnerable states: Remember, DEET is safe in pregnancy. Zika is not. 

Stay tuned next week for more breaking news from the world of Obstetrics and Gynecology.